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An integrative pan-cancer analysis revealing the difference in small ring finger family of SCF E3 ubiquitin ligases
BACKGROUND: The SCF (Skp1-cullin-F-box proteins) complex is the largest family of E3 ubiquitin ligases that mediate multiple specific substrate proteins degradation. Two ring-finger family members RBX1/ROC1 and RBX2/RNF7/SAG are small molecular proteins necessary for ubiquitin ligation activity of t...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434121/ https://www.ncbi.nlm.nih.gov/pubmed/36059474 http://dx.doi.org/10.3389/fimmu.2022.968777 |