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Redox homeostasis modulation using theranostic AIE nanoparticles results in positive-feedback drug accumulation and enhanced drug penetration to combat drug-resistant cancer

Drug-resistant cancers usually have multiple barriers to compromise the effect of therapies, of which multidrug-resistance (MDR) phenotype as the intracellular barrier and dense tumor matrix as the extracellular barrier, significantly contribute to the poor anticancer performance of current drug del...

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Detalles Bibliográficos
Autores principales: Chen, Shaoqing, Wang, Ziyu, Liu, Li, Li, Yuting, Ni, Xinye, Yuan, Hong, Wang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434132/
https://www.ncbi.nlm.nih.gov/pubmed/36060105
http://dx.doi.org/10.1016/j.mtbio.2022.100396