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Premature translation of the Drosophila zygotic genome activator Zelda is not sufficient to precociously activate gene expression

Following fertilization, the unified germ cells rapidly transition to a totipotent embryo. Maternally deposited mRNAs encode the proteins necessary for this reprogramming as the zygotic genome remains transcriptionally quiescent during the initial stages of development. The transcription factors req...

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Detalles Bibliográficos
Autores principales: Larson, Elizabeth D, Komori, Hideyuki, Fitzpatrick, Zoe A, Krabbenhoft, Samuel D, Lee, Cheng-Yu, Harrison, Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434156/
https://www.ncbi.nlm.nih.gov/pubmed/35876878
http://dx.doi.org/10.1093/g3journal/jkac159