Transmembrane helices 5 and 12 control transport dynamics, substrate affinity, and specificity in the elevator-type UapA transporter

An increasing number of solute transporters have been shown to function with the so-called sliding-elevator mechanism. Despite structural and functional differences, all elevator-type transporters use a common mechanism of substrate translocation via reversible movements of a mobile core domain (the...

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Detalles Bibliográficos
Autores principales: Dimakis, Dimitris, Pyrris, Yiannis, Diallinas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434233/
https://www.ncbi.nlm.nih.gov/pubmed/35894659
http://dx.doi.org/10.1093/genetics/iyac107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434233/
https://www.ncbi.nlm.nih.gov/pubmed/35894659
http://dx.doi.org/10.1093/genetics/iyac107

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