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IL-36γ is secreted through an unconventional pathway using the Gasdermin D and P2X7R membrane pores
Mucosal innate immunity functions as the first line of defense against invading pathogens. Members of the IL-1 family are key cytokines upregulated in the inflamed mucosa. Inflammatory cytokines are regulated by limiting their function and availability through their activation and secretion mechanis...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434278/ https://www.ncbi.nlm.nih.gov/pubmed/36059446 http://dx.doi.org/10.3389/fimmu.2022.979749 |