IL-36γ is secreted through an unconventional pathway using the Gasdermin D and P2X7R membrane pores

Mucosal innate immunity functions as the first line of defense against invading pathogens. Members of the IL-1 family are key cytokines upregulated in the inflamed mucosa. Inflammatory cytokines are regulated by limiting their function and availability through their activation and secretion mechanis...

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Detalles Bibliográficos
Autores principales: Manzanares-Meza, Laura D., Gutiérrez-Román, Claudia I., Jiménez-Pineda, Albertana, Castro-Martínez, Felipe, Patiño-López, Genaro, Rodríguez-Arellano, Eunice, Valle-Rios, Ricardo, Ortíz-Navarrete, Vianney F., Medina-Contreras, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434278/
https://www.ncbi.nlm.nih.gov/pubmed/36059446
http://dx.doi.org/10.3389/fimmu.2022.979749

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