Acquisition of cross-azole tolerance and aneuploidy in Candida albicans strains evolved to posaconazole

A number of in vitro studies have examined the acquisition of drug resistance to the triazole fluconazole, a first-line treatment for many Candida infections. Much less is known about posaconazole, a newer triazole. We conducted the first in vitro experimental evolution of replicates from 8 diverse...

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Detalles Bibliográficos
Autores principales: Kukurudz, Rebekah J, Chapel, Madison, Wonitowy, Quinn, Adamu Bukari, Abdul-Rahman, Sidney, Brooke, Sierhuis, Riley, Gerstein, Aleeza C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434289/
https://www.ncbi.nlm.nih.gov/pubmed/35881695
http://dx.doi.org/10.1093/g3journal/jkac156

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434289/
https://www.ncbi.nlm.nih.gov/pubmed/35881695
http://dx.doi.org/10.1093/g3journal/jkac156

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