Escape from recognition of SARS-CoV-2 Beta variant spike epitopes but overall preservation of T cell immunity

SARS-CoV-2 variants have emerged that escape neutralization and potentially impact vaccine efficacy. T cell responses play a role in protection from reinfection and severe disease, but the potential for spike mutations to affect T cell immunity is incompletely understood. We assessed neutralizing an...

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Detalles Bibliográficos
Autores principales: Riou, Catherine, Keeton, Roanne, Moyo-Gwete, Thandeka, Hermanus, Tandile, Kgagudi, Prudence, Baguma, Richard, Valley-Omar, Ziyaad, Smith, Mikhail, Tegally, Houriiyah, Doolabh, Deelan, Iranzadeh, Arash, Tyers, Lynn, Mutavhatsindi, Hygon, Tincho, Marius B., Benede, Ntombi, Marais, Gert, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, du Bruyn, Elsa, Stek, Cari, de Oliveira, Tulio, Williamson, Carolyn, Moore, Penny L., Wilkinson, Robert J., Ntusi, Ntobeko A. B., Burgers, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434381/
https://www.ncbi.nlm.nih.gov/pubmed/34931886
http://dx.doi.org/10.1126/scitranslmed.abj6824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434381/
https://www.ncbi.nlm.nih.gov/pubmed/34931886
http://dx.doi.org/10.1126/scitranslmed.abj6824

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