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Dysregulation of ACE-1 in Normal Aging and the Early Stages of Alzheimer’s Disease

An imbalance in the renin–angiotensin system (RAS) is associated with cognitive decline and disease pathology in Alzheimer’s disease (AD). In this study, we have investigated changes in the brain angiotensin-converting enzyme-1 (ACE-1) and angiotensin-II (Ang-II), and the counter-regulatory angioten...

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Detalles Bibliográficos
Autores principales: MacLachlan, Robert, Kehoe, Patrick Gavin, Miners, J Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434468/
https://www.ncbi.nlm.nih.gov/pubmed/35396835
http://dx.doi.org/10.1093/gerona/glac083