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Methamphetamine signals transcription of IL1β and TNFα in a reactive oxygen species-dependent manner and interacts with HIV-1 Tat to decrease antioxidant defense mechanisms
Methamphetamine (Meth) abuse is a common HIV co-morbidity that is linked to aggravated Central Nervous System (CNS) inflammation, which accentuates HIV- associated neurological disorders, triggered both directly or indirectly by the drug. We used the well-established human innate immune macrophage c...
Autores principales: | Basova, Liana V., Vien, Whitney, Bortell, Nikki, Najera, Julia A., Marcondes, Maria Cecilia Garibaldi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434488/ https://www.ncbi.nlm.nih.gov/pubmed/36060276 http://dx.doi.org/10.3389/fncel.2022.911060 |
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