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ELEVATE – evaluating Temozolomide and Nivolumab in patients with advanced unresectable previously treated oesophagogastric adenocarcinoma with MGMT methylation: study protocol for a single arm phase II trial

BACKGROUND: For patients with oesophagogastric adenocarcinoma, surgery is the only curative option and despite the use of multimodality therapy, which combines it with chemotherapy and/or radiotherapy, more than 50% of patients will relapse and die. Many UK patients present with advanced disease whi...

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Detalles Bibliográficos
Autores principales: Smyth, Elizabeth, Cozens, Kelly, Griffiths, Daniel, Clark, Kathryn L., Ewings, Sean, Petty, Russell, Underwood, Tim, Fitzgerald, Rebecca C., Tanner, James, Giger, Olivier, Anand, Shubha, Griffiths, Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434527/
https://www.ncbi.nlm.nih.gov/pubmed/36050653
http://dx.doi.org/10.1186/s12885-022-09891-9