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Combination of anti‐CD25 antibody and poly I:C treatment in pregnant NOD mice may be used as ‘pregnancy‐related’ type 1 diabetes model

AIMS/INTRODUCTION: Some women develop type 1 diabetes during pregnancy or immediately after delivery. However, the underlying pathophysiology remains largely unknown, probably because of the lack of a suitable animal model. In this study, we administered pregnant NOD mice with an anti‐CD25 antibody...

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Detalles Bibliográficos
Autores principales: Shimada, Akira, Toda, Kyoko, Inoue, Ikuo, Yamada, Taketo, Oikawa, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434566/
https://www.ncbi.nlm.nih.gov/pubmed/35533022
http://dx.doi.org/10.1111/jdi.13829