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Spontaneous xenogeneic GvHD in Wilms' tumor Patient‐Derived xenograft models and potential solutions

Severely immunocompromised NOD.Cg‐Prkdc ( scid ) Il2rg ( tm1Sug ) (NOG) mice are among the ideal animal recipients for generation of human cancer models. Transplantation of human solid tumors having abundant tumor‐infiltrating lymphocytes (TILs) can induce xenogeneic graft‐versus‐host disease (xGvHD...

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Detalles Bibliográficos
Autores principales: Monzavi, Seyed Mostafa, Muhammadnejad, Ahad, Behfar, Maryam, Khorsand, Amir Arsalan, Muhammadnejad, Samad, Kajbafzadeh, Abdol‐Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434572/
https://www.ncbi.nlm.nih.gov/pubmed/35726155
http://dx.doi.org/10.1002/ame2.12254