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Curcumin Interacts with α-Synuclein Condensates To Inhibit Amyloid Aggregation under Phase Separation
[Image: see text] The amyloid aggregation of α-synuclein (α-Syn) is highly associated with Parkinson’s disease (PD). Discovering α-Syn amyloid inhibitors is one of the strategies for PD therapies. Recent studies suggested that α-Syn undergoes phase separation to accelerate amyloid aggregation. Molec...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434619/ https://www.ncbi.nlm.nih.gov/pubmed/36061735 http://dx.doi.org/10.1021/acsomega.2c03534 |