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Hydrogel-Embedded Poly(Lactic-co-Glycolic Acid) Microspheres for the Delivery of hMSC-Derived Exosomes to Promote Bioactive Annulus Fibrosus Repair

OBJECTIVE: Intervertebral disk degeneration is a prevalent postoperative complication after discectomy, underscoring the need to develop preventative and bioactive treatment strategies that decelerate degeneration and seal annulus fibrosus (AF) defects. Human mesenchymal stem cell–derived exosomes (...

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Detalles Bibliográficos
Autores principales: DiStefano, Tyler J., Vaso, Keti, Panebianco, Christopher J., Danias, George, Chionuma, Henry N., Kunnath, Kuriakose, Karoulias, Stylianos Z., Wang, Minghui, Xu, Peng, Davé, Rajesh N., Sahoo, Susmita, Weiser, Jennifer R., Iatridis, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434687/
https://www.ncbi.nlm.nih.gov/pubmed/36040157
http://dx.doi.org/10.1177/19476035221113959