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Ambra1 deficiency impairs mitophagy in skeletal muscle

BACKGROUND: Maintaining healthy mitochondria is mandatory for muscle viability and function. An essential surveillance mechanism targeting defective and harmful mitochondria to degradation is the selective form of autophagy called mitophagy. Ambra1 is a multifaceted protein with well‐known autophagi...

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Detalles Bibliográficos
Autores principales: Gambarotto, Lisa, Metti, Samuele, Chrisam, Martina, Cerqua, Cristina, Sabatelli, Patrizia, Armani, Andrea, Zanon, Carlo, Spizzotin, Marianna, Castagnaro, Silvia, Strappazzon, Flavie, Grumati, Paolo, Cescon, Matilde, Braghetta, Paola, Trevisson, Eva, Cecconi, Francesco, Bonaldo, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434724/
https://www.ncbi.nlm.nih.gov/pubmed/35593053
http://dx.doi.org/10.1002/jcsm.13010