Stereoselective Olefination with Sterically Demanding Julia–Kocienski Reagents: Total Synthesis of Oxo-prothracarcin, Oxo-tomaymycin, and Boseongazepine B

[Image: see text] Total syntheses of three pyrrolo[1,4]benzodiazepine anticancer antibiotic family members oxo-prothracarcin, oxo-tomaymycin, and boseongazepine B are described. The total syntheses feature late-stage stereoselective olefination employing modified Julia–Kocienski reagents that can be...

Descripción completa

Detalles Bibliográficos
Autores principales: Leitis, Zigma̅rs, Sakaine, Guna, Kine̅ns, Artis, Smits, Gints
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434771/
https://www.ncbi.nlm.nih.gov/pubmed/36061714
http://dx.doi.org/10.1021/acsomega.2c03732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434771/
https://www.ncbi.nlm.nih.gov/pubmed/36061714
http://dx.doi.org/10.1021/acsomega.2c03732

Ejemplares similares