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Catalyst- and Additive-Free C(sp(3))–H Functionalization of (Thio)barbituric Acids via C-5 Dehydrogenative Aza-Coupling Under Ambient Conditions

[Image: see text] A one-pot room-temperature-based three-component reaction strategy has been accomplished to access a new series of bio-relevant barbituric/2-thiobarbituric acid hydrazones from the reaction between barbituric/2-thiobarbituric acids, primary aromatic amines, and tert-butyl nitrite i...

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Detalles Bibliográficos
Autores principales: Brahmachari, Goutam, Bhowmick, Anindita, Karmakar, Indrajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434791/
https://www.ncbi.nlm.nih.gov/pubmed/36061699
http://dx.doi.org/10.1021/acsomega.2c03073