Selinexor inhibits growth of patient derived chordomas in vivo as a single agent and in combination with abemaciclib through diverse mechanisms

Chordoma is a rare cancer that grows in the base of the skull and along the mobile spine from remnants of embryonic notochord tissue. The cornerstone of current treatments is surgical excision with adjuvant radiation therapy, although complete surgical removal is not always possible. Chordomas have...

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Detalles Bibliográficos
Autores principales: Walker, Christopher J., Chang, Hua, Henegar, Leah, Kashyap, Trinayan, Shacham, Sharon, Sommer, Josh, Wick, Michael J., Levy, Joan, Landesman, Yosef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434827/
https://www.ncbi.nlm.nih.gov/pubmed/36059685
http://dx.doi.org/10.3389/fonc.2022.808021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434827/
https://www.ncbi.nlm.nih.gov/pubmed/36059685
http://dx.doi.org/10.3389/fonc.2022.808021

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