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IL-27 shapes the immune properties of human astrocytes and their impact on encountered human T lymphocytes

BACKGROUND: Interleukin-27 (IL-27) can trigger both pro- and anti-inflammatory responses. This cytokine is elevated in the central nervous system (CNS) of multiple sclerosis (MS) patients, but how it influences neuroinflammatory processes remains unclear. As astrocytes express the receptor for IL-27...

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Detalles Bibliográficos
Autores principales: Lemaître, Florent, Farzam-kia, Negar, Carmena Moratalla, Ana, Carpentier Solorio, Yves, Clenet, Marie-Laure, Tastet, Olivier, Cleret-Buhot, Aurélie, Guimond, Jean Victor, Haddad, Elie, Duquette, Pierre, Girard, J. Marc, Prat, Alexandre, Larochelle, Catherine, Arbour, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434874/
https://www.ncbi.nlm.nih.gov/pubmed/36050707
http://dx.doi.org/10.1186/s12974-022-02572-1