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Transcriptome profiling of microRNAs reveals potential mechanisms of manual therapy alleviating neuropathic pain through microRNA-547-3p-mediated Map4k4/NF-κb signaling pathway

BACKGROUND: Local neuroinflammation secondary to spinal nerve compression in lumbar disk herniation (LDH) is a key driver contributing to neuropathic pain. Manual therapy (MT), a widely used nonsurgical therapy, can relieve LDH-mediated pain by reducing inflammation. MT has attracted extensive atten...

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Detalles Bibliográficos
Autores principales: Yao, Chongjie, Ren, Jun, Huang, Ruixin, Tang, Cheng, Cheng, Yanbin, Lv, Zhizhen, Kong, Lingjun, Fang, Sitong, Tao, Jiming, Fu, Yangyang, Zhu, Qingguang, Fang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434879/
https://www.ncbi.nlm.nih.gov/pubmed/36045396
http://dx.doi.org/10.1186/s12974-022-02568-x