Decreased Levels of DNA Methylation in the PCDHA Gene Cluster as a Risk Factor for Early-Onset High Myopia in Young Children

PURPOSE: High myopia (HM), an eye disorder with at least –6.0 diopters refractive error, has a complex etiology with environmental, genetic, and likely epigenetic factors involved. To complement the DNA methylation assessment in children with HM, we analyzed genes that had significantly lower DNA me...

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Detalles Bibliográficos
Autores principales: Swierkowska, Joanna, Karolak, Justyna A., Vishweswaraiah, Sangeetha, Mrugacz, Malgorzata, Radhakrishna, Uppala, Gajecka, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434983/
https://www.ncbi.nlm.nih.gov/pubmed/36036911
http://dx.doi.org/10.1167/iovs.63.9.31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434983/
https://www.ncbi.nlm.nih.gov/pubmed/36036911
http://dx.doi.org/10.1167/iovs.63.9.31

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