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Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis

PURPOSE: Tight junctions (TJs) form the structural basis of retinal pigment epithelium (RPE) barrier functions. Although oxidative stress contributes to age-related macular degeneration, it is unclear how RPE TJ integrity is controlled by redox balance. In this study, we investigated the protective...

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Detalles Bibliográficos
Autores principales: Jiang, Yida, Duan, Li-Juan, Pi, Jingbo, Le, Yun-Zheng, Fong, Guo-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434985/
https://www.ncbi.nlm.nih.gov/pubmed/36036912
http://dx.doi.org/10.1167/iovs.63.9.30