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Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis
PURPOSE: Tight junctions (TJs) form the structural basis of retinal pigment epithelium (RPE) barrier functions. Although oxidative stress contributes to age-related macular degeneration, it is unclear how RPE TJ integrity is controlled by redox balance. In this study, we investigated the protective...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434985/ https://www.ncbi.nlm.nih.gov/pubmed/36036912 http://dx.doi.org/10.1167/iovs.63.9.30 |