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Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution

A remarkable number of SARS‐CoV‐2 variants and other as yet unmonitored lineages harbor amino‐acid substitutions with the potential to modulate the interface between the spike receptor‐binding domain (RBD) and its receptor ACE2. The naturally occurring Q498Y substitution, which is present in current...

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Detalles Bibliográficos
Autores principales: Erausquin, Elena, Glaser, Fabian, Fernández-Recio, Juan, López-Sagaseta, Jacinto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435600/
https://www.ncbi.nlm.nih.gov/pubmed/36048155
http://dx.doi.org/10.1107/S2059798322007677