Cargando…
Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution
A remarkable number of SARS‐CoV‐2 variants and other as yet unmonitored lineages harbor amino‐acid substitutions with the potential to modulate the interface between the spike receptor‐binding domain (RBD) and its receptor ACE2. The naturally occurring Q498Y substitution, which is present in current...
Autores principales: | Erausquin, Elena, Glaser, Fabian, Fernández-Recio, Juan, López-Sagaseta, Jacinto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435600/ https://www.ncbi.nlm.nih.gov/pubmed/36048155 http://dx.doi.org/10.1107/S2059798322007677 |
Ejemplares similares
-
Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice
por: Huang, Kun, et al.
Publicado: (2021) -
Structural plasticity in I-A(g7) links autoreactivity to hybrid insulin peptides in type I diabetes
por: Erausquin, Elena, et al.
Publicado: (2022) -
Identification of a broad lipid repertoire associated to the endothelial cell protein C receptor (EPCR)
por: Erausquin, Elena, et al.
Publicado: (2022) -
Spike residue 403 affects binding of coronavirus spikes to human ACE2
por: Zech, Fabian, et al.
Publicado: (2021) -
498 Mastocytosis and IgE-dependent Sensitization: Report of 2 Cases
por: Toche, Paola, et al.
Publicado: (2012)