FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation

FcγRIIB is an inhibitory receptor expressed throughout B cell development. Diminished expression or function is associated with lupus in mice and humans, in particular through an effect on autoantibody production and plasma cell (PC) differentiation. Here, we analyzed the effect of B cell–intrinsic...

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Detalles Bibliográficos
Autores principales: Barlev, Ashley N., Malkiel, Susan, Kurata-Sato, Izumi, Dorjée, Annemarie L., Suurmond, Jolien, Diamond, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435648/
https://www.ncbi.nlm.nih.gov/pubmed/35819855
http://dx.doi.org/10.1172/JCI157250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435648/
https://www.ncbi.nlm.nih.gov/pubmed/35819855
http://dx.doi.org/10.1172/JCI157250

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