Human β-defensin-3 attenuates atopic dermatitis–like inflammation through autophagy activation and the aryl hydrocarbon receptor signaling pathway

Human β-defensin-3 (hBD-3) exhibits antimicrobial and immunomodulatory activities; however, its contribution to autophagy regulation remains unclear, and the role of autophagy in the regulation of the epidermal barrier in atopic dermatitis (AD) is poorly understood. Here, keratinocyte autophagy was...

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Detalles Bibliográficos
Autores principales: Peng, Ge, Tsukamoto, Saya, Ikutama, Risa, Nguyen, Hai Le Thanh, Umehara, Yoshie, Trujillo-Paez, Juan V., Yue, Hainan, Takahashi, Miho, Ogawa, Takasuke, Kishi, Ryoma, Tominaga, Mitsutoshi, Takamori, Kenji, Kitaura, Jiro, Kageyama, Shun, Komatsu, Masaaki, Okumura, Ko, Ogawa, Hideoki, Ikeda, Shigaku, Niyonsaba, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435650/
https://www.ncbi.nlm.nih.gov/pubmed/35834333
http://dx.doi.org/10.1172/JCI156501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435650/
https://www.ncbi.nlm.nih.gov/pubmed/35834333
http://dx.doi.org/10.1172/JCI156501

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