The epithelial-specific ER stress sensor ERN2/IRE1β enables host-microbiota crosstalk to affect colon goblet cell development

Epithelial cells lining mucosal surfaces of the gastrointestinal and respiratory tracts uniquely express ERN2/IRE1β, a paralogue of the most evolutionarily conserved endoplasmic reticulum stress sensor, ERN1/IRE1α. How ERN2 functions at the host-environment interface and why a second paralogue evolv...

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Detalles Bibliográficos
Autores principales: Grey, Michael J., De Luca, Heidi, Ward, Doyle V., Kreulen, Irini A.M., Bugda Gwilt, Katlynn, Foley, Sage E., Thiagarajah, Jay R., McCormick, Beth A., Turner, Jerrold R., Lencer, Wayne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435652/
https://www.ncbi.nlm.nih.gov/pubmed/35727638
http://dx.doi.org/10.1172/JCI153519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435652/
https://www.ncbi.nlm.nih.gov/pubmed/35727638
http://dx.doi.org/10.1172/JCI153519

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