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High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes

The advent of massively parallel sequencing revealed extensive transcription beyond protein-coding genes, identifying tens of thousands of long noncoding RNAs (lncRNAs). Selected functional examples raised the possibility that lncRNAs, as a class, may maintain broad regulatory roles. Expression of l...

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Detalles Bibliográficos
Autores principales: Muskovic, Walter, Slavich, Eve, Maslen, Ben, Kaczorowski, Dominik C., Cursons, Joseph, Crampin, Edmund, Kavallaris, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435739/
https://www.ncbi.nlm.nih.gov/pubmed/35760562
http://dx.doi.org/10.1101/gr.276818.122