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Thousands of human mutation clusters are explained by short-range template switching
Variation within human genomes is unevenly distributed, and variants show spatial clustering. DNA replication–related template switching is a poorly known mutational mechanism capable of causing major chromosomal rearrangements as well as creating short inverted sequence copies that appear as local...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435742/ https://www.ncbi.nlm.nih.gov/pubmed/35760560 http://dx.doi.org/10.1101/gr.276478.121 |