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Assembly of a pangenome for global cattle reveals missing sequences and novel structural variations, providing new insights into their diversity and evolutionary history

A cattle pangenome representation was created based on the genome sequences of 898 cattle representing 57 breeds. The pangenome identified 83 Mb of sequence not found in the cattle reference genome, representing 3.1% novel sequence compared with the 2.71-Gb reference. A catalog of structural variant...

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Detalles Bibliográficos
Autores principales: Zhou, Yang, Yang, Lv, Han, Xiaotao, Han, Jiazheng, Hu, Yan, Li, Fan, Xia, Han, Peng, Lingwei, Boschiero, Clarissa, Rosen, Benjamin D., Bickhart, Derek M., Zhang, Shujun, Guo, Aizhen, Van Tassell, Curtis P., Smith, Timothy P.L., Yang, Liguo, Liu, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435747/
https://www.ncbi.nlm.nih.gov/pubmed/35977842
http://dx.doi.org/10.1101/gr.276550.122