Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling

The development of cancer therapies may be improved by the discovery of tumor-specific molecular dependencies. The requisite tools include genetic and chemical perturbations, each with its strengths and limitations. Chemical perturbations can be readily applied to primary cancer samples at large sca...

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Detalles Bibliográficos
Autores principales: Batzilla, Alina, Lu, Junyan, Kivioja, Jarno, Putzker, Kerstin, Lewis, Joe, Zenz, Thorsten, Huber, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436053/
https://www.ncbi.nlm.nih.gov/pubmed/35994503
http://dx.doi.org/10.1371/journal.pcbi.1010438

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436053/
https://www.ncbi.nlm.nih.gov/pubmed/35994503
http://dx.doi.org/10.1371/journal.pcbi.1010438

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