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Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling
The development of cancer therapies may be improved by the discovery of tumor-specific molecular dependencies. The requisite tools include genetic and chemical perturbations, each with its strengths and limitations. Chemical perturbations can be readily applied to primary cancer samples at large sca...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436053/ https://www.ncbi.nlm.nih.gov/pubmed/35994503 http://dx.doi.org/10.1371/journal.pcbi.1010438 |