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The muscle proteome reflects changes in mitochondrial function, cellular stress and proteolysis after 14 days of unilateral lower limb immobilization in active young men

Skeletal muscle unloading due to joint immobilization induces muscle atrophy, which has primarily been attributed to reductions in protein synthesis in humans. However, no study has evaluated the skeletal muscle proteome response to limb immobilization using SWATH proteomic methods. This study chara...

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Detalles Bibliográficos
Autores principales: Doering, Thomas M., Thompson, Jamie-Lee M., Budiono, Boris P., MacKenzie-Shalders, Kristen L., Zaw, Thiri, Ashton, Kevin J., Coffey, Vernon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436066/
https://www.ncbi.nlm.nih.gov/pubmed/36048851
http://dx.doi.org/10.1371/journal.pone.0273925