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The muscle proteome reflects changes in mitochondrial function, cellular stress and proteolysis after 14 days of unilateral lower limb immobilization in active young men
Skeletal muscle unloading due to joint immobilization induces muscle atrophy, which has primarily been attributed to reductions in protein synthesis in humans. However, no study has evaluated the skeletal muscle proteome response to limb immobilization using SWATH proteomic methods. This study chara...
Autores principales: | Doering, Thomas M., Thompson, Jamie-Lee M., Budiono, Boris P., MacKenzie-Shalders, Kristen L., Zaw, Thiri, Ashton, Kevin J., Coffey, Vernon G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436066/ https://www.ncbi.nlm.nih.gov/pubmed/36048851 http://dx.doi.org/10.1371/journal.pone.0273925 |
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