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TNF-α and NF-κB signaling play a critical role in cigarette smoke-induced epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is characterized by the growth and contraction of cellular membranes within the vitreous cavity and on both surfaces of the retina, resulting in recurrent retinal detachments and poor visual outcomes. Proinflammatory cytokines like tumor necrosis factor alpha (T...

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Detalles Bibliográficos
Autores principales: Wang, Victor, Heffer, Alison, Roztocil, Elisa, Feldon, Steven E., Libby, Richard T., Woeller, Collynn F., Kuriyan, Ajay E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436090/
https://www.ncbi.nlm.nih.gov/pubmed/36048826
http://dx.doi.org/10.1371/journal.pone.0271950