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SPEACH_AF: Sampling protein ensembles and conformational heterogeneity with Alphafold2

The unprecedented performance of Deepmind’s Alphafold2 in predicting protein structure in CASP XIV and the creation of a database of structures for multiple proteomes and protein sequence repositories is reshaping structural biology. However, because this database returns a single structure, it brou...

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Detalles Bibliográficos
Autores principales: Stein, Richard A., Mchaourab, Hassane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436118/
https://www.ncbi.nlm.nih.gov/pubmed/35994486
http://dx.doi.org/10.1371/journal.pcbi.1010483