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SPEACH_AF: Sampling protein ensembles and conformational heterogeneity with Alphafold2
The unprecedented performance of Deepmind’s Alphafold2 in predicting protein structure in CASP XIV and the creation of a database of structures for multiple proteomes and protein sequence repositories is reshaping structural biology. However, because this database returns a single structure, it brou...
Autores principales: | Stein, Richard A., Mchaourab, Hassane S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436118/ https://www.ncbi.nlm.nih.gov/pubmed/35994486 http://dx.doi.org/10.1371/journal.pcbi.1010483 |
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