Cargando…

Glucocorticoid induces GSDMD-dependent pyrolysis in PC12 cells via endoplasmic reticulum stress

OBJECTIVE: The present study explored whether pyroptosis is involved in the injury process of PC12 cells induced by glucocorticoid (GC) and the regulatory relationship between endoplasmic reticulum stress (ERS) and pyrolysis. METHODS: LDH leakage of PC12 cells was detected by LDH assay. The number o...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Bin, Zhang, Tengteng, Wei, Lai, Zhao, Bin, Wang, Qingzhi, Yao, Zhijun, Yi, Shanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436126/
https://www.ncbi.nlm.nih.gov/pubmed/36048803
http://dx.doi.org/10.1371/journal.pone.0274057