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Glucocorticoid induces GSDMD-dependent pyrolysis in PC12 cells via endoplasmic reticulum stress
OBJECTIVE: The present study explored whether pyroptosis is involved in the injury process of PC12 cells induced by glucocorticoid (GC) and the regulatory relationship between endoplasmic reticulum stress (ERS) and pyrolysis. METHODS: LDH leakage of PC12 cells was detected by LDH assay. The number o...
Autores principales: | Yang, Bin, Zhang, Tengteng, Wei, Lai, Zhao, Bin, Wang, Qingzhi, Yao, Zhijun, Yi, Shanyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436126/ https://www.ncbi.nlm.nih.gov/pubmed/36048803 http://dx.doi.org/10.1371/journal.pone.0274057 |
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