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Quantitation of phosphohistidine in proteins in a mammalian cell line by (31)P NMR

There is growing evidence to suggest that phosphohistidines are present at significant levels in mammalian cells and play a part in regulating cellular activity, in particular signaling pathways related to cancer. Because of the chemical instability of phosphohistidine at neutral or acid pH, it rema...

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Detalles Bibliográficos
Autores principales: Makwana, Mehul V., Williamson, Mike P., Jackson, Richard F. W., Muimo, Richmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436146/
https://www.ncbi.nlm.nih.gov/pubmed/36048825
http://dx.doi.org/10.1371/journal.pone.0273797