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Antioxidant mitoquinone ameliorates EtOH-LPS induced lung injury by inhibiting mitophagy and NLRP3 inflammasome activation

Chronic ethanol abuse is a systemic disorder and a risk factor for acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD). However, the mechanisms involved are unknown. One explanation is that ethanol produces damaging reactive oxygen species (ROS) and disturbs t...

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Detalles Bibliográficos
Autores principales: Sang, Wenhua, Chen, Sha, Lin, Lidan, Wang, Nan, Kong, Xiaoxia, Ye, Jinyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436256/
https://www.ncbi.nlm.nih.gov/pubmed/36059543
http://dx.doi.org/10.3389/fimmu.2022.973108