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In vitro reconstitution of calcium-dependent recruitment of the human ESCRT machinery in lysosomal membrane repair

The endosomal sorting complex required for transport (ESCRT) machinery is centrally involved in the repair of damage to both the plasma and lysosome membranes. ESCRT recruitment to sites of damage occurs on a fast time scale, and Ca(2+) has been proposed to play a key signaling role in the process....

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Detalles Bibliográficos
Autores principales: Shukla, Sankalp, Larsen, Kevin P., Ou, Chenxi, Rose, Kevin, Hurley, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436306/
https://www.ncbi.nlm.nih.gov/pubmed/35994655
http://dx.doi.org/10.1073/pnas.2205590119