Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome

Albuminuria is a hallmark of glomerular disease of various etiologies. It is not only a symptom of glomerular disease but also a cause leading to glomerulosclerosis, interstitial fibrosis, and eventually, a decline in kidney function. The molecular mechanism underlying albuminuria-induced kidney inj...

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Detalles Bibliográficos
Autores principales: Park, Sun-Ji, Kim, Yeawon, Li, Chuang, Suh, Junwoo, Sivapackiam, Jothilingam, Goncalves, Tassia M., Jarad, George, Zhao, Guoyan, Urano, Fumihiko, Sharma, Vijay, Chen, Ying Maggie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436335/
https://www.ncbi.nlm.nih.gov/pubmed/35994650
http://dx.doi.org/10.1073/pnas.2116505119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436335/
https://www.ncbi.nlm.nih.gov/pubmed/35994650
http://dx.doi.org/10.1073/pnas.2116505119

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