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TPL2 kinase expression is regulated by the p38γ/p38δ-dependent association of aconitase-1 with TPL2 mRNA

p38γ and p38δ (p38γ/p38δ) regulate inflammation, in part by controlling tumor progression locus 2 (TPL2) expression in myeloid cells. Here, we demonstrate that TPL2 protein levels are dramatically reduced in p38γ/p38δ-deficient (p38γ/δ(−/−)) cells and tissues without affecting TPL2 messenger ribonuc...

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Detalles Bibliográficos
Autores principales:	Escós, Alejandra, Martín-Gómez, José, González-Romero, Diego, Díaz-Mora, Ester, Francisco-Velilla, Rosario, Santiago, Cesar, Cuezva, José M., Domínguez-Zorita, Sonia, Martínez-Salas, Encarnación, Sonenberg, Nahum, Sanz-Ezquerro, Juan José, Jafarnejad, Seyed Mehdi, Cuenda, Ana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436348/ https://www.ncbi.nlm.nih.gov/pubmed/35994673 http://dx.doi.org/10.1073/pnas.2204752119

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