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Injury-induced MAPK activation triggers body axis formation in Hydra by default Wnt signaling

Hydra’s almost unlimited regenerative potential is based on Wnt signaling, but so far it is unknown how the injury stimulus is transmitted to discrete patterning fates in head and foot regenerates. We previously identified mitogen-activated protein kinases (MAPKs) among the earliest injury response...

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Detalles Bibliográficos
Autores principales: Tursch, Anja, Bartsch, Natascha, Mercker, Moritz, Schlüter, Jana, Lommel, Mark, Marciniak-Czochra, Anna, Özbek, Suat, Holstein, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436372/
https://www.ncbi.nlm.nih.gov/pubmed/35994642
http://dx.doi.org/10.1073/pnas.2204122119