Cargando…

Multi-step recognition of potential 5' splice sites by the Saccharomyces cerevisiae U1 snRNP

In eukaryotes, splice sites define the introns of pre-mRNAs and must be recognized and excised with nucleotide precision by the spliceosome to make the correct mRNA product. In one of the earliest steps of spliceosome assembly, the U1 small nuclear ribonucleoprotein (snRNP) recognizes the 5' sp...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansen, Sarah R, White, David S, Scalf, Mark, Corrêa, Ivan R, Smith, Lloyd M, Hoskins, Aaron A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436412/
https://www.ncbi.nlm.nih.gov/pubmed/35959885
http://dx.doi.org/10.7554/eLife.70534