Cargando…

Generation of three iPSC lines from dilated cardiomyopathy patients carrying a pathogenic LMNA variant

LMNA-related dilated cardiomyopathy (DCM) is caused by pathogenic variants in LMNA and is characterized by left ventricular enlargement, reduced systolic function, and arrhythmia. Here, we generated three human induced pluripotent stem cell (iPSC) lines from peripheral blood mononuclear cells (PBMCs...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Chelsea, Cho, Sangkyun, Lai, Celine, Shenoy, Sushma, Vagelos, Randall, Wu, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436418/
https://www.ncbi.nlm.nih.gov/pubmed/34954454
http://dx.doi.org/10.1016/j.scr.2021.102638