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Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression

T helper 17 (Th17) cells subtype of non-T2 asthma is less responsive (resistant) to inhaled corticosteroids (ICS), so also called severe asthma. Methyl-CpG-binding domain protein 2 (MBD2) regulates the differentiation of the Th17 cells, showing the possibility of a therapeutic target in severe asthm...

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Detalles Bibliográficos
Autores principales: Wasti, Binaya, Chen, Zhifeng, Yuan, Yu, He, Yi, Duan, Wentao, Jia, Jingsi, Li, Danhong, Xiao, Bing, Li, Jianmin, Liu, Yi, Liu, Shaokun, Zhang, Dongshan, Zhang, Xiufeng, Ma, Libing, Xiang, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436621/
https://www.ncbi.nlm.nih.gov/pubmed/36062195
http://dx.doi.org/10.1155/2022/3096528