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Androgen Plays a Potential Novel Hormonal Therapeutic Role in Th17 Cells Predominant Neutrophilic Severe Asthma by Attenuating BECs Regulated Th17 Cells Differentiation via MBD2 Expression
T helper 17 (Th17) cells subtype of non-T2 asthma is less responsive (resistant) to inhaled corticosteroids (ICS), so also called severe asthma. Methyl-CpG-binding domain protein 2 (MBD2) regulates the differentiation of the Th17 cells, showing the possibility of a therapeutic target in severe asthm...
Autores principales: | Wasti, Binaya, Chen, Zhifeng, Yuan, Yu, He, Yi, Duan, Wentao, Jia, Jingsi, Li, Danhong, Xiao, Bing, Li, Jianmin, Liu, Yi, Liu, Shaokun, Zhang, Dongshan, Zhang, Xiufeng, Ma, Libing, Xiang, Xudong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436621/ https://www.ncbi.nlm.nih.gov/pubmed/36062195 http://dx.doi.org/10.1155/2022/3096528 |
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